Computational Genomics Group - University of Bristol
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SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes. The SUPERFAMILY annotation is based on a collection of hidden Markov models. Which represent structural protein domains at the SCOP. A superfamily groups together domains which have an evolutionary relationship. The annotation is produced by scanning protein sequences from over 2,478 completely sequenced genomes. Against the hidden Markov models. Submit sequences for SCOP classification.
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An open-source R package for omics data integrative analysis in terms of. Network-based sample classifications and visualisations on 2D sample landscape;. Random Walk with Restart for network affinity calculation;. Enrichment analysis using a variety of built-in databases;. A wide variety of built-in RData.
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Computational Genomics Group - University of BristolDESCRIPTION
A leading UK based Bioinformatics and Computational Genomics group. Our group focuses on the analysis and assignment of SCOP structural protein domains to all sequenced genomes with protein annotations. For further information on SCOP assignment please visit our online resource SUPERFAMILY at httpsupfam.org. The groups research themes include genome scale phylogenetic reconstruction, functional and phenotypic assignment of novel proteins, cell reprogramming and transcriptional regulation, detection andPARSED CONTENT
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